LMPD Database

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LMP009784

UniProt Annotations

Entry Information
Gene Nameacyl-coenzyme A oxidase 3
Protein EntryACOX3_ARATH
UniProt IDP0CZ23
SpeciesArabidopsis
Comments
Comment typeDescription
Biophysicochemical PropertiesKinetic parameters: KM=3.7 uM for lauroyl-CoA; pH dependence: Optimum pH is 8.5-9.0.;
Catalytic ActivityAcyl-CoA + O(2) = trans-2,3-dehydroacyl-CoA + H(2)O(2).
CofactorName=FAD; Xref=ChEBI:CHEBI:57692;
Developmental StageInduced by seed imbibition with a peak at day 2 and then declines steadily until day 7. Not detected in developing seeds. Constitutive expression in root axis. {ECO:0000269|PubMed:10859203}.
FunctionCatalyzes the desaturation of medium-chain acyl-CoAs to 2-trans-enoyl-CoAs. Active on C8:0- to C14:0-CoA with a maximal activity on C12:0-CoA.
InductionNot induced by dehydration or abscisic acid (ABA). {ECO:0000269|PubMed:15141068}.
PathwayLipid metabolism; peroxisomal fatty acid beta-oxidation.
SimilarityBelongs to the acyl-CoA oxidase family. {ECO:0000305}.
Subcellular LocationPeroxisome {ECO:0000269|PubMed:10918060}.
Tissue SpecificityMost abundant in flowers and senescing rosette leaves. Lower expression in hypocotyls, stems, young rosette leaves, cotyledons, cauline leaves and root tip of young seedlings. {ECO:0000269|PubMed:10859203, ECO:0000269|PubMed:10918060}.