LMPD Database

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LMP009809

UniProt Annotations

Entry Information
Gene Namealdo-keto reductase family 4 member C8
Protein EntryAKRC8_ARATH
UniProt IDO80944
SpeciesArabidopsis
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=3; Name=1; IsoId=O80944-1; Sequence=Displayed; Name=2; IsoId=O80944-2; Sequence=VSP_040012, VSP_040015; Note=Derived from EST data. No experimental confirmation available.; Name=3; IsoId=O80944-3; Sequence=VSP_040013, VSP_040014; Note=Derived from EST data. No experimental confirmation available.;
Biophysicochemical PropertiesKinetic parameters: KM=4.4 uM for 9,10-phenanthrenequinone {ECO:0000269|PubMed:19616008}; KM=35 uM for isatin {ECO:0000269|PubMed:19616008}; KM=1.6 mM for glyoxal {ECO:0000269|PubMed:19616008}; KM=3.3 mM for methylglyoxal {ECO:0000269|PubMed:19616008}; KM=22.4 mM for glyceraldehyde {ECO:0000269|PubMed:19616008};
FunctionOxidoreductase acting on a broad range of substrates: reduces ketosteroids, aromatic aldehydes, ketones, sugars and other aliphatic aldehydes, and oxidizes hydroxysteroids. May function as detoxifiying enzyme by reducing a range of toxic aldehydes and ketones produced during stress. {ECO:0000269|PubMed:19616008}.
InductionBy drought, salt and cold stresses. {ECO:0000269|PubMed:19616008}.
SimilarityBelongs to the aldo/keto reductase family. {ECO:0000305}.