LMPD Database

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LMP009851

UniProt Annotations

Entry Information
Gene Nameannexin 1
Protein EntryANXD1_ARATH
UniProt IDQ9SYT0
SpeciesArabidopsis
Comments
Comment typeDescription
Biophysicochemical PropertiespH dependence: Active at pH 7.0 and 9.0, but not at pH 5.5. {ECO:0000269|PubMed:16153598};
Developmental StageExpressed in the elongation zone of the root and in the root cap in germinating seedlings. Expressed later in the internal cells of the root and in the epidermal cells and the vascular tissue of the hypocotyl. By day 7, expressed in the initiating trichomes on leaf primordia and in the vasculature of hypocotyl and cotyledon. At the transition to reproductive growth (day 14), expressed in the vasculature, epidermis, basal mesophyll cells and pith meristem of leaves. {ECO:0000269|PubMed:11457958, ECO:0000269|PubMed:15368128}.
Disruption PhenotypePlants are hypersensitive to osmotic stress and abscisic acid (ABA) during germination and early seedling growth. {ECO:0000269|PubMed:15161963}.
DomainA pair of annexin repeats may form one binding site for calcium and phospholipid.
FunctionHas a peroxidase activity. May act in counteracting oxidative stress. May also mediate regulated, targeted secretion of Golgi-derived vesicles during seedling development. {ECO:0000269|PubMed:15368128, ECO:0000269|PubMed:16153598}.
InductionUp-regulated by cold, dehydration, salt, osmotic and oxidative stresses. Up-regulated by abscisic acid (ABA) and salicylic acid (SA). {ECO:0000269|PubMed:15161963, ECO:0000269|PubMed:16531057, ECO:0000269|PubMed:8855345}.
MiscellaneousBinds lipids at millimolar calcium concentration.
PtmPhosphorylated.
SimilarityBelongs to the annexin (TC 1.A.31.1) family. {ECO:0000305}.
SimilarityContains 4 annexin repeats. {ECO:0000305}.
Subcellular LocationCytoplasm, cytosol. Membrane. Note=translocate from cytosol to membrane upon salt treatment; this translocation is calcium dependent.
SubunitMonomer and homodimer. {ECO:0000269|PubMed:16153598}.
Tissue SpecificityUbiquitous. Most abundant in stems. {ECO:0000269|PubMed:15368128, ECO:0000269|PubMed:8855345}.