LMPD Database

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LMP010013

UniProt Annotations

Entry Information
Gene Namecarotene epsilon-monooxygenase
Protein EntryLUT1_ARATH
UniProt IDQ6TBX7
SpeciesArabidopsis
Comments
Comment typeDescription
Catalytic ActivityAlpha-carotene + O(2) + AH(2) = alpha- cryptoxanthin + A + H(2)O.
CofactorName=heme; Xref=ChEBI:CHEBI:30413; Evidence={ECO:0000250};
Disruption PhenotypeNo visible phenotype, but lacks lutein and accumulates high levels of zeinoxanthin and beta, beta- xanthophylls. Triple mutant CYP97C1-BCH1-BCH2 is paler and smaller than wild-type. {ECO:0000269|PubMed:12782726, ECO:0000269|PubMed:14709673, ECO:0000269|PubMed:16890225, ECO:0000269|PubMed:18466360}.
FunctionHeme-containing cytochrome P450 involved in the biosynthesis of xanthophylls. Specific for epsilon- and beta-ring hydroxylation of alpha-carotene. Has only a low activity toward the beta-rings of beta-carotene. The preferred substrate in planta is not alpha-carotene but the epsilon-ring of zeinoxanthin. {ECO:0000269|PubMed:12782726, ECO:0000269|PubMed:16890225, ECO:0000269|PubMed:19147649, ECO:0000269|PubMed:19939422}.
Sequence CautionSequence=AAM13903.1; Type=Erroneous initiation; Note=Translation N-terminally shortened.; Evidence={ECO:0000305}; Sequence=CAB64216.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
SimilarityBelongs to the cytochrome P450 family. {ECO:0000305}.
Subcellular LocationPlastid, chloroplast membrane {ECO:0000269|PubMed:20061580}.