LMPD Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
LMP010071

UniProt Annotations

Entry Information
Gene Namecytochrome P450, family 711, subfamily A, polypeptide 1
Protein EntryMAX1_ARATH
UniProt IDB9DFU2
SpeciesArabidopsis
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=B9DFU2-1; Sequence=Displayed; Name=2; IsoId=B9DFU2-2; Sequence=VSP_046323;
CofactorName=heme; Xref=ChEBI:CHEBI:30413; Evidence={ECO:0000250};
Disruption PhenotypeIncreased shoot branching. {ECO:0000269|PubMed:15737939, ECO:0000269|PubMed:16387852, ECO:0000269|PubMed:20667910, ECO:0000269|PubMed:21119045, ECO:0000269|PubMed:23204501}.
FunctionActs downstream of CCD7/MAX3 and CCD8/MAX4 in strigolactone signaling pathway and may be implicated in synthesis of carotenoid-derived branch regulators. Acts as a positive regulator of the flavonoid pathway in the late vegetative stage plant. Strigolactones are hormones that inhibit tillering and shoot branching through the MAX-dependent pathway, contribute to the regulation of shoot architectural response to phosphate- limiting conditions and function as rhizosphere signal that stimulates hyphal branching of arbuscular mycorrhizal fungi and trigger seed germination of root parasitic weeds. {ECO:0000269|PubMed:15737939, ECO:0000269|PubMed:16387852}.
MiscellaneousThe branching phenotypes of the max1, ccd7/max3 and ccd8/max4 mutants can be rescued by exogenous treatment with the synthetic strigolactone analogs GR24 and 4BD. {ECO:0000305|PubMed:23204501}.
Sequence CautionSequence=AAL91286.1; Type=Frameshift; Positions=102; Evidence={ECO:0000305};
SimilarityBelongs to the cytochrome P450 family. {ECO:0000305}.
Subcellular LocationMembrane {ECO:0000305}; Single-pass membrane protein.
Tissue SpecificityExpressed in the vascular cylinder (including the pericycle) in roots, the cambial region of vascular bundles in inflorescence stems and the vascular junctions of axillary regions in leaves and flowers. {ECO:0000269|PubMed:15737939}.