LMPD Database

LMP010134

UniProt Annotations

Entry Information
Gene Namediacylglycerol kinase 7
Protein EntryDGK7_ARATH
UniProt IDF4JQ95
SpeciesArabidopsis
Comments
Comment typeDescription
Biophysicochemical PropertiesKinetic parameters: KM=0.74 mM for ATP {ECO:0000269|PubMed:16081412}; Vmax=0.34 pmol/min/ug enzyme toward 1,2-dioleoyl-sn-glycerol {ECO:0000269|PubMed:16081412}; pH dependence: Optimum pH is 6.8. {ECO:0000269|PubMed:16081412};
Catalytic ActivityATP + 1,2-diacyl-sn-glycerol = ADP + 1,2- diacyl-sn-glycerol 3-phosphate. {ECO:0000269|PubMed:16081412}.
FunctionPhosphorylates the second messenger diacylglycerol (DAG) to generate phosphatidic acid (PA), another important signaling molecule. PA is required for plant development and responses to abiotic stress and pathogen attack. May be involved in the accumulation of PA during cold stress xhibits high specificity for 1,2-dioleoyl-sn-glycerol (1,2-DOG), 1-palmitoyl, 2-oleoyl-sn- glycerol (1,2 POG), 1-stearoyl, 2-linoleoyl-sn-glycerol (1,2-SLG) and 1-oleoyl, 2-palmitoyl-sn-glycerol (1,2-OPG). {ECO:0000269|PubMed:16081412, ECO:0000269|PubMed:23346092}.
Sequence CautionSequence=AAK25884.1; Type=Miscellaneous discrepancy; Note=Intron retention.; Evidence={ECO:0000305}; Sequence=AAM44963.1; Type=Miscellaneous discrepancy; Note=Intron retention.; Evidence={ECO:0000305}; Sequence=AAU04880.1; Type=Miscellaneous discrepancy; Note=Intron retention.; Evidence={ECO:0000305}; Sequence=CAB81027.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
SimilarityBelongs to the eukaryotic diacylglycerol kinase family. {ECO:0000305}.
SimilarityContains 1 DAGKc domain. {ECO:0000255|PROSITE- ProRule:PRU00783}.
SubunitMonomer. {ECO:0000250}.
Tissue SpecificityHighly expressed in flowers, and at low levels in roots, stems and leaves. {ECO:0000269|PubMed:16081412}.