LMPD Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
LMP010209

UniProt Annotations

Entry Information
Gene Namefarnesylcysteine lyase
Protein EntryPCYOX_ARATH
UniProt IDP57681
SpeciesArabidopsis
Comments
Comment typeDescription
Catalytic ActivityS-(2E,6E)-farnesyl-L-cysteine + O(2) + H(2)O = (2E,6E)-farnesal + L-cysteine + H(2)O(2). {ECO:0000269|PubMed:17425716}.
CofactorName=FAD; Xref=ChEBI:CHEBI:57692; Evidence={ECO:0000250};
FunctionInvolved in the degradation of prenylcysteine. Cleaves specifically the thioether bond of S-farnesyl-L-cysteine and has no activity with S-geranylgeranyl-L-cysteine. Recognizes also N- acetyl-farnesylcysteine and may have a role in deprenylation of farnesylated proteins. {ECO:0000269|PubMed:17425716}.
MiscellaneousPlants with decreased levels of farnesylcysteine lyase exhibit delayed germination and hypersensitivity to abscisic acid.
SimilarityBelongs to the prenylcysteine oxidase family. {ECO:0000305}.
Subcellular LocationLysosome {ECO:0000250}.
Tissue SpecificityExpressed in seedilings, flowers, stems, leaves and roots. {ECO:0000269|PubMed:17425716}.