LMPD Database

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LMP010211

UniProt Annotations

Entry Information
Gene Namefatty acid hydroxylase 1
Protein EntryFAH1_ARATH
UniProt IDO48916
SpeciesArabidopsis
Comments
Comment typeDescription
FunctionFatty acid 2-hydroxylase involved in the alpha- hydroxylation of sphingolipid-associated very long-chain fatty acids (VLCFA). Probably involved in the resistance response to oxidative stress. {ECO:0000269|PubMed:22635113, ECO:0000269|PubMed:9353282}.
InductionUp-regulated by H(2)O(2) treatment. {ECO:0000269|PubMed:22635113}.
SimilarityBelongs to the sterol desaturase family. {ECO:0000305}.
Subcellular LocationEndoplasmic reticulum membrane {ECO:0000269|PubMed:22635113}; Multi-pass membrane protein {ECO:0000269|PubMed:22635113}.
SubunitInteracts with CYTB5-A, CYTB5-B, CYTB5-C and CYTB5-D. Interacts indirectly with BI-1 via CYTB5-D. {ECO:0000269|PubMed:19054355, ECO:0000269|PubMed:22635113}.