LMPD Database

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LMP010504

UniProt Annotations

Entry Information
Gene Nameinositol polyphosphate multikinase beta
Protein EntryIPMKB_ARATH
UniProt IDQ9FLT2
SpeciesArabidopsis
Comments
Comment typeDescription
Catalytic Activity2 ATP + 1D-myo-inositol 1,4,5-trisphosphate = 2 ADP + 1D-myo-inositol 1,3,4,5,6-pentakisphosphate.
Catalytic ActivityATP + 1D-myo-inositol 1,3,4,6- tetrakisphosphate = ADP + 1D-myo-inositol 1,3,4,5,6- pentakisphosphate.
Developmental StageExpressed in mature pollen, but not in immature pollen grains. {ECO:0000269|PubMed:12566584}.
Disruption PhenotypeLoss-of-function mutant atIpk2beta-1 (T-DNA insertion) is fully complemented by AtIPK2alpha in tissue but not in seeds, leading to the generation of phytate-free seeds. {ECO:0000269|PubMed:16107538}.
FunctionInositol phosphate kinase with a broad substrate specificity. Phosphorylates inositol 1,4,5-trisphosphate (Ins(1,4,5)P3), inositol 1,4,5,6-tetrakisphosphate (Ins(1,4,5,6)P4), inositol 1,3,4,5-tetrakisphosphate (Ins(1,3,4,5)P4), inositol 1,3,4,6-tetrakisphosphate (Ins(1,3,4,6)P4) and inositol 1,2,3,4,6-pentakisphosphate (Ins(1,2,3,4,6)P5) but not inositol 1,4-bisphosphate (Ins(1,4)P2), inositol 1,3,4-trisphosphate (Ins(1,3,4)P3), inositol 1,2,6- trisphosphate (Ins(1,2,6)P3), inositol 3,4,5,6-tetrakisphosphate (Ins(3,4,5,6)P4), inositol 1,3,4,5,6-pentakisphosphate (Ins(1,3,4,5,6)P5), inositol 1,2,4,5,6-pentakisphosphate (Ins(1,2,4,5,6)P5) or inositol hexakisphosphate (InsP6). Involved in the auxin signaling pathway. Regulates axillary shoot branching and is required for phytate synthesis in seeds. {ECO:0000269|PubMed:12226109, ECO:0000269|PubMed:16107538, ECO:0000269|PubMed:17434984}.
InductionInduced by auxin, but not by salt, abscisic acid, manitol, water or drought. {ECO:0000269|PubMed:12566584, ECO:0000269|PubMed:17434984}.
MiscellaneousDoes not bind calmodulin.
PtmPhosphorylated. {ECO:0000269|PubMed:12566584}.
SimilarityBelongs to the inositol phosphokinase (IPK) family. {ECO:0000305}.
Subcellular LocationNucleus {ECO:0000269|PubMed:12566584}.
Tissue SpecificityExpressed in leaves, stems, roots, siliques and flowers. Detected in vascular strands, stigma cells, the abscission zones of fully elongated siliques, the root central cylinder and the root tip. {ECO:0000269|PubMed:12226109, ECO:0000269|PubMed:12566584}.