LMPD Database

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LMP010624

UniProt Annotations

Entry Information
Gene Namemevalonate kinase
Protein EntryKIME_ARATH
UniProt IDP46086
SpeciesArabidopsis
Comments
Comment typeDescription
Catalytic ActivityATP + (R)-mevalonate = ADP + (R)-5- phosphomevalonate.
Enzyme RegulationIts activity is inhibited in vitro by geranyl pyrophosphate (GPP) and farnesyl pyrophosphate (FPP) that bind competitively at the ATP-binding site on the enzyme.
PathwayIsoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via mevalonate pathway; isopentenyl diphosphate from (R)-mevalonate: step 1/3.
Sequence CautionSequence=AAD45421.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
SimilarityBelongs to the GHMP kinase family. Mevalonate kinase subfamily. {ECO:0000305}.
Subcellular LocationCytoplasm {ECO:0000305}.