LMPD Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
LMP010643

UniProt Annotations

Entry Information
Gene NameN-acylphosphatidylethanolamine synthase
Protein EntryNAPES_ARATH
UniProt IDQ9ZV87
SpeciesArabidopsis
Comments
Comment typeDescription
Developmental StageIn imbibed seeds, accumulates in cotyledons and hypocotyls. In flowers, expressed in the filament of stamens, in the style, and in ovary with eggs of pistil. {ECO:0000269|PubMed:19447891}.
DomainThe HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphocholine. {ECO:0000250}.
FunctionAcyltransferase that catalyzes the N-acylation of phosphatidylethanolamine to form N-acylphosphatidylethanolamine (N-acyl-PE) (e.g. NAPEs containing C16:0, C16:1, C18:0, and C18:1). Mediates also the formation of acylphosphatidylglycerol (acyl-PG) from lysoglycerophospholipid by O-acylation. Uses acyl- CoA as acyl donors. Acylates 1-acyllysophosphatidylethanolamine (1-acyllyso-PE) and 1-acyllysophosphatidylglycerol (1-acyllyso-PG) at the sn-2-position. {ECO:0000269|PubMed:19447891, ECO:0000269|PubMed:21803774}.
Sequence CautionSequence=AAK76548.1; Type=Frameshift; Positions=143; Evidence={ECO:0000305};
SimilarityBelongs to the taffazin family. {ECO:0000305}.
Subcellular LocationCell membrane {ECO:0000269|PubMed:19447891}; Single-pass membrane protein {ECO:0000269|PubMed:19447891}.
Tissue SpecificityEssentially present in young tissues. Expressed in roots, cotyledons, leaves, and shoot and root apical meristems. {ECO:0000269|PubMed:19447891}.