LMPD Database

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LMP010659

UniProt Annotations

Entry Information
Gene Nameglycosylphosphatidylinositol-anchored lipid protein transfer 1
Protein EntryLTPG1_ARATH
UniProt IDQ9C7F7
SpeciesArabidopsis
Comments
Comment typeDescription
Developmental StageHigh levels in the aerial portion of 10 days old seedlings. Accumulates in the epidermis during cuticle biosynthesis (e.g. in inflorescence stems). Also detected in flowers, in upper portion of the styles, pollen, veins of the sepals and petals, silique walls and seeds in the early stages of development. In epidermis, present in trichomes, leaf mesophyll cells, and stem cortex and xylem. {ECO:0000269|PubMed:19321705, ECO:0000269|PubMed:19366900}.
Disruption PhenotypeReduced cuticular wax load on the stem surface and in silique walls, with altered cuticular lipid composition (especially C29 alkane) associated with diffuse cuticular layer structure. Increased number of plastoglobules in the stem cortex and leaf mesophyll cells, protrusions of the cytoplasm into the vacuole in the epidermis, and enhanced susceptibility to infection by the necrotrophic fungal pathogen Alternaria brassicicola. {ECO:0000269|PubMed:19321705, ECO:0000269|PubMed:19366900, ECO:0000269|PubMed:22891199}.
FunctionLipid transfer protein that, together with LTPG2, binds to lipids and functions as a component of the cuticular lipid export machinery that performs extensive export of intracellular lipids (e.g. C29 alkane) from epidermal cells to the surface to build the cuticular wax layer and silique walls. Involved in the establishment of resistance to the necrotrophic fungal pathogen Alternaria brassicicola. {ECO:0000269|PubMed:19321705, ECO:0000269|PubMed:19366900, ECO:0000269|PubMed:22891199}.
PtmO-glycosylated on hydroxyprolines; noncontiguous hydroxylproline residues are glycosylated with arabinogalactan. {ECO:0000250}.
SimilarityBelongs to the plant LTP family. {ECO:0000305}.
Subcellular LocationCell membrane; Lipid-anchor, GPI-anchor. Secreted, cell wall. Endoplasmic reticulum. Golgi apparatus. Note=Targeted to the plasma membrane via the vesicular trafficking system. Localized to the plasma membrane on all faces of epidermal cells. Also detected in the periclinal cell wall. In young meristematic cells, observed in plasma membrane and in puncta resembling the Golgi.
Tissue SpecificityUp-regulated in the epidermis of stems and leaves. Expressed in the epidermis, stem cortex, vascular bundles and mesophyll cells in root tips, seedlings, leaves, caulines, flowers, siliques, pollen, and early-developing seeds. {ECO:0000269|PubMed:16299169, ECO:0000269|PubMed:19321705}.