LMPD Database

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LMP010705

UniProt Annotations

Entry Information
Gene NamefatA acyl-ACP thioesterase
Protein EntryFATA1_ARATH
UniProt IDQ42561
SpeciesArabidopsis
Comments
Comment typeDescription
Biophysicochemical PropertiesKinetic parameters: KM=13.9 uM for myristoyl-ACP (14:0-ACP) {ECO:0000269|PubMed:12061798}; KM=8.9 uM for myristoleoyl-ACP (14:1-ACP) {ECO:0000269|PubMed:12061798}; KM=4.9 uM for palmitoyl-ACP (16:0-ACP) {ECO:0000269|PubMed:12061798}; KM=4.9 uM for palmitoleoyl-ACP (16:1-ACP) {ECO:0000269|PubMed:12061798}; KM=5.0 uM for stearoyl-ACP (18:0-ACP) {ECO:0000269|PubMed:12061798}; KM=3.1 uM for oleoyl-ACP (18:1-ACP) {ECO:0000269|PubMed:12061798}; Note=The catalytic efficiency for 18:1 is at least 20-fold higher than for other substrates.;
Catalytic ActivityOleoyl-[acyl-carrier-protein] + H(2)O = [acyl- carrier-protein] + oleate. {ECO:0000269|PubMed:12061798}.
FunctionPlays an essential role in chain termination during de novo fatty acid synthesis. Possesses high thioesterase activity for oleoyl-ACP versus other acyl-ACPs. Substrate preference is 18:1 > 18:0 > 16:1. {ECO:0000269|PubMed:12061798, ECO:0000269|PubMed:22002626}.
SimilarityBelongs to the acyl-ACP thioesterase family. {ECO:0000305}.
Subcellular LocationPlastid, chloroplast {ECO:0000305}.