LMPD Database

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LMP010851

UniProt Annotations

Entry Information
Gene Namephosphoinositide phospholipase C 7
Protein EntryPLCD7_ARATH
UniProt IDQ9LY51
SpeciesArabidopsis
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=Q9LY51-1; Sequence=Displayed; Note=No experimental confirmation available.; Name=2; IsoId=Q9LY51-2; Sequence=VSP_032149, VSP_032150; Note=No experimental confirmation available. Potentially inactive.;
Catalytic Activity1-phosphatidyl-1D-myo-inositol 4,5- bisphosphate + H(2)O = 1D-myo-inositol 1,4,5-trisphosphate + diacylglycerol.
CofactorName=Ca(2+); Xref=ChEBI:CHEBI:29108;
FunctionThe production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. {ECO:0000250}.
SimilarityContains 1 C2 domain. {ECO:0000255|PROSITE- ProRule:PRU00041}.
SimilarityContains 1 EF-hand-like domain. {ECO:0000305}.
SimilarityContains 1 PI-PLC X-box domain. {ECO:0000255|PROSITE- ProRule:PRU00270}.
SimilarityContains 1 PI-PLC Y-box domain. {ECO:0000255|PROSITE- ProRule:PRU00271}.
Subcellular LocationCell membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.
Tissue SpecificityExpressed in leaves, roots, flowers and siliques. {ECO:0000269|Ref.3}.