LMPD Database

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LMP010944

UniProt Annotations

Entry Information
Gene Namelysophosphatidyl acyltransferase 4
Protein EntryLPAT4_ARATH
UniProt IDQ8L4Y2
SpeciesArabidopsis
Comments
Comment typeDescription
Catalytic ActivityAcyl-CoA + 1-acyl-sn-glycerol 3-phosphate = CoA + 1,2-diacyl-sn-glycerol 3-phosphate.
DomainThe HXXXXD motif is essential for acyltransferase activity and may constitute the binding site for the phosphate moiety of the glycerol-3-phosphate. {ECO:0000250}.
FunctionMay convert lysophosphatidic acid (LPA) into phosphatidic acid by incorporating acyl moiety at the 2 position (By similarity). Has no activity when expressed in bacteria or yeast. {ECO:0000250}.
PathwayPhospholipid metabolism; CDP-diacylglycerol biosynthesis; CDP-diacylglycerol from sn-glycerol 3-phosphate: step 2/3.
Sequence CautionSequence=AAD55275.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=AAG51931.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
SimilarityBelongs to the 1-acyl-sn-glycerol-3-phosphate acyltransferase family. {ECO:0000305}.
Subcellular LocationMembrane {ECO:0000305}; Multi-pass membrane protein {ECO:0000305}.
Tissue SpecificityWidely expressed at low level. {ECO:0000269|PubMed:15772283}.