LMPD Database

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LMP011069

UniProt Annotations

Entry Information
Gene Namecarotenoid isomerase
Protein EntryCRTSO_ARATH
UniProt IDQ9M9Y8
SpeciesArabidopsis
Comments
Comment typeDescription
Catalytic Activity7,9,7',9'-tetra-cis-lycopene = all-trans- lycopene. {ECO:0000269|PubMed:11884677}.
CofactorName=NAD(+); Xref=ChEBI:CHEBI:57540; Evidence={ECO:0000250}; Name=NADP(+); Xref=ChEBI:CHEBI:58349; Evidence={ECO:0000250}; Name=FAD; Xref=ChEBI:CHEBI:57692; Evidence={ECO:0000250};
FunctionCarotene cis-trans-isomerase that converts 7,9,9'-tri- cis-neurosporene to 9'-cis-neurosporene and 7,9,9',7'-tetra-cis- lycopene (also known as prolycopene) into all-trans-lycopene. Isomerization requires redox-active components, suggesting that isomerization is achieved by a reversible redox reaction acting at specific double bonds. Isomerizes adjacent cis-double bonds at C7 and C9 pairwise into the trans-configuration, but is incapable of isomerizing single cis-double bonds at C9 and C9'. Carotenoid biosynthesis is partly required to form the prolamellar bodies of etioplasts. {ECO:0000269|PubMed:11884677}.
PathwayCarotenoid biosynthesis; lycopene biosynthesis. {ECO:0000269|PubMed:11884677}.
Sequence CautionSequence=AAF63149.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
SimilarityBelongs to the carotenoid/retinoid oxidoreductase family. CrtISO subfamily. {ECO:0000305}.
Subcellular LocationPlastid, chloroplast membrane {ECO:0000250}; Peripheral membrane protein {ECO:0000250}.