LMPD Database

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LMP011122

UniProt Annotations

Entry Information
Gene Nameprotein LUTEIN DEFICIENT 5
Protein EntryLUT5_ARATH
UniProt IDQ93VK5
SpeciesArabidopsis
Comments
Comment typeDescription
CofactorName=heme; Xref=ChEBI:CHEBI:30413; Evidence={ECO:0000250};
Disruption PhenotypeAccumulation of alpha-carotene and alpha- cryptoxanthin. Triple mutant CYP97A3-BCH1-BCH2 has a highly retarded growth. {ECO:0000269|PubMed:16492736, ECO:0000269|PubMed:16890225}.
FunctionHeme-containing cytochrome P450 involved in the biosynthesis of xanthophylls. Specific for beta-ring hydroxylation of alpha- and beta-carotene. Has also a low activity toward the epsilon-rings of alpha-carotene. The beta-ring of alpha-carotene is the preferred substrate in planta. {ECO:0000269|PubMed:16492736, ECO:0000269|PubMed:16890225, ECO:0000269|PubMed:19147649}.
MiscellaneousAlpha-carotene is incorporated into photosystems in lut5 mutants.
Sequence CautionSequence=AAG50718.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305};
SimilarityBelongs to the cytochrome P450 family. {ECO:0000305}.
Subcellular LocationPlastid, chloroplast membrane {ECO:0000269|PubMed:20061580}.