LMPD Database

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LMP011269

UniProt Annotations

Entry Information
Gene Nameserine/threonine-protein kinase BRI1-like 1
Protein EntryBRL1_ARATH
UniProt IDQ9ZWC8
SpeciesArabidopsis
Comments
Comment typeDescription
Catalytic ActivityATP + a protein = ADP + a phosphoprotein.
DomainA 70 amino acid island between the 19th and the 20th LRR is essential for the binding of brassinosteroids. {ECO:0000250}.
DomainContains two pairs of conservatively spaced Cys (Cys pair 1 and 2) possibly involved in forming some heterodimers. {ECO:0000250}.
FunctionReceptor with a serine/threonine-protein kinase activity. Regulates, in response to brassinosteroid binding, a signaling cascade involved in plant development. Binds brassinolide. May be involved in cell growth and vascular differentiation. {ECO:0000269|PubMed:15469497, ECO:0000269|PubMed:15486337}.
InteractionQ94F62:BAK1; NbExp=5; IntAct=EBI-590903, EBI-617138; Q9FMZ0:BKI1; NbExp=4; IntAct=EBI-590903, EBI-1111615;
SimilarityBelongs to the protein kinase superfamily. Ser/Thr protein kinase family. {ECO:0000255|PROSITE-ProRule:PRU00159}.
SimilarityContains 1 protein kinase domain. {ECO:0000255|PROSITE-ProRule:PRU00159}.
SimilarityContains 23 LRR (leucine-rich) repeats. {ECO:0000305}.
Subcellular LocationCell membrane {ECO:0000269|PubMed:15486337}; Single-pass type I membrane protein {ECO:0000269|PubMed:15486337}.
Tissue SpecificityPredominantly expressed in vascular tissues. From 7 day old seedlings, it is expressed in the columella cells of the root tip, in the vascular initials in the meristematic region of the root and in vascular tissues. After germination, it is expressed in the stele cell and in the early differentiation zone of the root, where the expression continues from the root to the hypocotyls and cotyledons following the midvein. In mature plants, it is expressed in the vasculature of the leaf, predominantly in the midvein, and in the vascular bundles of inflorescence stems. Localizes to procambial cells of the vascular bundles located between the differentiating xylem and the phloem. {ECO:0000269|PubMed:15469497, ECO:0000269|PubMed:15486337}.
Web ResourceName=PlantP kinase Classification PPC; URL="http://plantsp.genomics.purdue.edu/family/class.html";