LMPD Database

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LMP011422

UniProt Annotations

Entry Information
Gene Namealternative oxidase protein IMMUTANS
Protein EntryAOX4_ARATH
UniProt IDQ56X52
SpeciesArabidopsis
Comments
Comment typeDescription
Catalytic Activity2 ubiquinol + O(2) = 2 ubiquinone + 2 H(2)O. {ECO:0000269|PubMed:15032871, ECO:0000269|PubMed:16449381}.
CofactorName=Fe cation; Xref=ChEBI:CHEBI:24875; Note=Binds 2 iron ions per subunit.;
Developmental StageExpressed throughout the development of the leaves. {ECO:0000269|PubMed:14504923}.
Disruption PhenotypeVariegated cotyledons and leaves. The amount of white tissue increases with light intensity. {ECO:0000269|PubMed:7920709}.
FunctionActs early in chloroplast biogenesis as a component of a redox chain responsible for phytoene desaturation. Prevents the generation of toxic oxygen radicals and photooxidation of the nascent photosynthetic apparatus. Involved in the differentiation of multiple plastid types, including chloroplasts, amyloplasts, and etioplasts. Might participate in the chloroplast respiratory chain. {ECO:0000269|PubMed:10938359, ECO:0000269|PubMed:11553735, ECO:0000269|PubMed:14504923, ECO:0000269|PubMed:15032871, ECO:0000269|PubMed:16249174, ECO:0000269|PubMed:16449381, ECO:0000269|PubMed:19386811, ECO:0000269|PubMed:7920709, ECO:0000269|PubMed:9878631, ECO:0000269|PubMed:9878632}.
Sequence CautionSequence=BAD94037.1; Type=Erroneous initiation; Note=Translation N-terminally extended.; Evidence={ECO:0000305}; Sequence=CAA16776.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305}; Sequence=CAB79181.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
SimilarityBelongs to the alternative oxidase family. {ECO:0000305}.
Subcellular LocationPlastid, chloroplast thylakoid membrane; Multi-pass membrane protein; Stromal side. Plastid, chromoplast membrane; Multi-pass membrane protein. Note=localized to the stromal thylakoid lamellae. {ECO:0000269|PubMed:14504923}.
Tissue SpecificityUbiquitous. {ECO:0000269|PubMed:11553735}.