LMPD Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
LMP011446

UniProt Annotations

Entry Information
Gene Namezeta-carotene desaturase
Protein EntryZDS_ARATH
UniProt IDQ38893
SpeciesArabidopsis
Comments
Comment typeDescription
Catalytic Activity9,9'-di-cis-zeta-carotene + 2 quinone = 7,9,7',9'-tetra-cis-lycopene + 2 quinol. {ECO:0000269|PubMed:9914519}.
CofactorName=decylplastoquinone; Xref=ChEBI:CHEBI:72953; Evidence={ECO:0000250}; Name=6-decylubiquinone; Xref=ChEBI:CHEBI:52020; Evidence={ECO:0000250}; Note=Lipophilic quinones such as decyl-plastoquinone or decyl- ubiquinone. {ECO:0000250};
FunctionCatalyzes the conversion of zeta-carotene to lycopene via the intermediary of neurosporene. It carries out two consecutive desaturations (introduction of double bonds) at positions C-7 and C-7'. Shows stereoselectivity toward trans C15- C15'zeta-carotene double bond. The zeta-carotene produced by the phytoene desaturase PDS has a C15-C15' double bond in the cis configuration and it requires isomerization before being recognized as substrate by ZDS. The main product is 7,9,7',9'- tetra-cis-lycopene (pro-lycopene). {ECO:0000269|PubMed:9914519}.
PathwayCarotenoid biosynthesis; lycopene biosynthesis.
SimilarityBelongs to the zeta carotene desaturase family. {ECO:0000305}.
Subcellular LocationPlastid, chloroplast. Plastid, chromoplast.