LMPD Database

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LMP011498

UniProt Annotations

Entry Information
Gene Namesteroidogenic acute regulatory protein
Protein EntrySTAR_DANRE
UniProt IDQ9DG10
SpeciesZebrafish
Comments
Comment typeDescription
FunctionPlays a key role in steroid hormone synthesis by enhancing the metabolism of cholesterol into pregnenolone. Mediates the transfer of cholesterol from the outer mitochondrial membrane to the inner mitochondrial membrane where it is cleaved to pregnenolone (By similarity). {ECO:0000250}.
PathwaySteroid metabolism; cholesterol metabolism.
SimilarityContains 1 START domain. {ECO:0000255|PROSITE- ProRule:PRU00197}.
Subcellular LocationMitochondrion {ECO:0000250}.
Tissue SpecificityHighly expressed in the testis and at lower levels in the ovary, kidney and head.