LMPD Database

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LMP011524

UniProt Annotations

Entry Information
Gene Nameestrogen receptor 1
Protein EntryESR1_DANRE
UniProt IDP57717
SpeciesZebrafish
Comments
Comment typeDescription
DomainComposed of three domains: a modulating N-terminal domain, a DNA-binding domain and a C-terminal ligand-binding domain.
FunctionThe steroid hormones and their receptors are involved in the regulation of eukaryotic gene expression and affect cellular proliferation and differentiation in target tissues.
SimilarityBelongs to the nuclear hormone receptor family. NR3 subfamily. {ECO:0000305}.
SimilarityContains 1 nuclear receptor DNA-binding domain. {ECO:0000255|PROSITE-ProRule:PRU00407}.
Subcellular LocationNucleus.
SubunitBinds DNA as a homodimer. Can form a heterodimer with ER- beta (By similarity). {ECO:0000250}.