LMPD Database

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LMP011541

UniProt Annotations

Entry Information
Gene Namecholine phosphotransferase 1
Protein EntryCHPT1_DANRE
UniProt IDQ7ZW02
SpeciesZebrafish
Comments
Comment typeDescription
Catalytic ActivityCDP-choline + 1,2-diacyl-sn-glycerol = CMP + a phosphatidylcholine.
CofactorName=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250}; Name=Mn(2+); Xref=ChEBI:CHEBI:29035; Evidence={ECO:0000250};
FunctionCatalyzes phosphatidylcholine biosynthesis from CDP- choline. It thereby plays a central role in the formation and maintenance of vesicular membranes (By similarity). {ECO:0000250}.
PathwayPhospholipid metabolism; phosphatidylcholine biosynthesis; phosphatidylcholine from phosphocholine: step 2/2.
SimilarityBelongs to the CDP-alcohol phosphatidyltransferase class-I family. {ECO:0000305}.
Subcellular LocationGolgi apparatus membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.