LMPD Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
LMP011611

UniProt Annotations

Entry Information
Gene Nameunc-119 homolog 1
Protein EntryU119B_DANRE
UniProt IDQ90Z08
SpeciesZebrafish
Comments
Comment typeDescription
DomainAdopts an immunoglobulin-like beta-sandwich fold forming a hydrophobic cavity that capture N-terminally myristoylated target peptides. Phe residues within the hydrophobic beta sandwich are required for myristate binding (By similarity). {ECO:0000250}.
FunctionMyristoyl-binding protein that acts as a cargo adapter: specifically binds the myristoyl moiety of a subset of N- terminally myristoylated proteins and is required for their localization. Plays a key role in localization of proteins to the primary cilium membrane. {ECO:0000269|PubMed:22085962}.
SimilarityBelongs to the PDE6D/unc-119 family. {ECO:0000305}.
Subcellular LocationCell projection, cilium {ECO:0000250}.
Tissue SpecificityDetected in embryo. Detected in larvae four days after fertilization, in retina and neural tissues (at protein level). Detected in embryos at the sphere stage, during gastrulation, somitogenesis and in swimming larvae, both within and outside of the developing nervous system. Detected in adults. {ECO:0000269|PubMed:15593328}.