LMPD Database

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LMP012242

UniProt Annotations

Entry Information
Gene Namesulfotransferase family 1, cytosolic sulfotransferase 2
Protein EntryQ7ZUS4_DANRE
UniProt IDQ7ZUS4
SpeciesZebrafish
Comments
Comment typeDescription
Biophysicochemical PropertiespH dependence: Optimum pH is 4.75 and 10.5. These two pH optima may correspond to two distinct conformational states of the enzyme.; Temperature dependence: Active from 20 to 43 degrees Celsius.;
Enzyme RegulationInhibited by Co(2+), Zn(2+), Cd(2+) and Pb(2+) ions. Inactivated by Hg(2+) and Cu(2+) ions.
FunctionSulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) as sulfonate donor to catalyze the sulfate conjugation of a variety of xenobiotic and endogenous compounds, including 2-naphthol, hydroxychlorobiphenyls, T3 (triiodo-L- thyronine), T4 (thyroxine), estrone and DOPA.
SimilarityBelongs to the sulfotransferase 1 family.
Subcellular LocationCytoplasm.
Tissue SpecificityExpressed in liver.