LMPD Database

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LMP012384

Record overview

LMPD IDLMP012384
Gene ID50700
SpeciesHomo sapiens (Human)
Gene Nameretinol dehydrogenase 8 (all-trans)
Gene SymbolRDH8
SynonymsPRRDH; SDR28C2;
Chromosome19
Map Location19p13.2
EC Number1.1.1.300
SummaryThis gene encodes a member of the short-chain dehydrogenase/reductase family. The encoded protein catalyzes the reduction of all-trans-retinal to all-trans-retinol, the first reaction step of the rhodopsin regeneration pathway. This enzymatic reaction is the rate-limiting step in the visual cycle. [provided by RefSeq, Feb 2014]
OrthologsView orthologs and multiple alignments for RDH8

Proteins

retinol dehydrogenase 8
Refseq ID:NP_056540
Protein GI:393535067
UniProt ID:Q9NYR8
mRNA ID:NM_015725
Length:331
RefSeq Status:
MNGQSQVLPGGGHESREGINMAAAPRTVLISGCSSGIGLELAVQLAHDPKKRYQVVATMRDLGKKETLEAAAGEALGQTLTVAQLDVCSDESVAQCLSCI
QGEVDVLVNNAGMGLVGPLEGLSLAAMQNVFDTNFFGAVRLVKAVLPGMKRRRQGHIVVISSVMGLQGVIFNDVYAASKFALEGFFESLAIQLLQFNIFI
SLVEPGPVVTEFEGKLLAQVSMAEFPGTDPETLHYFRDLYLPASRKLFCSVGQNPQDVVQAIVNVISSTRPPLRRQTNIRYSPLTTLKTVDSSGSLYVRT
THRLLFRCPRLLNLGLQCLSCGCLPTRVRPR