LMPD Database

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LMP012385

UniProt Annotations

Entry Information
Gene Nameacetyl-CoA acyltransferase 1
Protein EntryTHIKA_RAT
UniProt IDP21775
SpeciesRat
Comments
Comment typeDescription
Alternative ProductsEvent=Alternative splicing; Named isoforms=2; Name=1; IsoId=P21775-1; Sequence=Displayed; Name=2; IsoId=P21775-2; Sequence=VSP_023746; Note=No experimental confirmation available.;
Catalytic ActivityAcyl-CoA + acetyl-CoA = CoA + 3-oxoacyl-CoA.
InductionPeroxisomal thiolase is markedly induced (at the level of transcription) by various hypolipidemic compounds in parallel with the other two enzymes of the peroxisomal beta-oxidation system.
PathwayLipid metabolism; fatty acid metabolism.
Sequence CautionSequence=AAA41471.1; Type=Erroneous initiation; Evidence= ; Sequence=AAH89821.1; Type=Erroneous initiation; Evidence= ; Sequence=BAA14106.1; Type=Erroneous initiation; Evidence= ;
SimilarityBelongs to the thiolase family
Subcellular LocationPeroxisome.
SubunitHomodimer.