LMPD Database

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LMP012391

Record overview

LMPD IDLMP012391
Gene ID24192
SpeciesMacaca mulata (Rhesus monkey)
Gene Namealdo-keto reductase family 1, member B1 (aldose reductase)
Gene SymbolAkr1b1
SynonymsAlr; Aldr1; ALDRED; Akr1b3; Akr1b4; ALR-P-I; RATALDRED;
Alternate namesaldose reductase; AR; aldo-keto reductase family 1, member B4 (aldose reductase); Aldehyde reductase 1 (low Km aldose reductase) (5.8 kb PstI fragment, probably the functional gene);
Chromosome4
Map Location4q22
EC Number1.1.1.21
Summaryregulates NF-kappa B mediated mitogenic signaling; may play a role in the polyol pathway [RGD, Feb 2006]
OrthologsView orthologs and multiple alignments for Akr1b1

Proteins

aldose reductase
Refseq ID:NP_036630
Protein GI:6978491
UniProt ID:P07943
mRNA ID:NM_012498
Length:316
RefSeq Status:
MASHLELNNGTKMPTLGLGTWKSPPGQVTEAVKVAIDMGYRHIDCAQVYQNEKEVGVALQEKLKEQVVKRQDLFIVSKLWCTFHDQSMVKGACQKTLSDL
QLDYLDLYLIHWPTGFKPGPDYFPLDASGNVIPSDTDFVDTWTAMEQLVDEGLVKAIGVSNFNPLQIERILNKPGLKYKPAVNQIECHPYLTQEKLIEYC
HCKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKEIAAKYNKTTAQVLIRFPIQRNLVVIPKSVTPARIAENFKVFDFELSNEDMATLLSYNRNWRVCA
LMSCAKHKDYPFHAEV