LMPD Database

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LMP012402

UniProt Annotations

Entry Information
Gene Namefatty acid binding protein 1, liver
Protein EntryFABPL_RAT
UniProt IDP02692
SpeciesRat
Comments
Comment typeDescription
DomainForms a beta-barrel structure that accommodates hydrophobic ligands in its interior.
FunctionBinds free fatty acids and their coenzyme A derivatives, bilirubin, and some other small molecules in the cytoplasm. May be involved in intracellular lipid transport.
InteractionP22449:Hnf4a; NbExp=3; IntAct=EBI-1209448, EBI-5261592;
MiscellaneousThere are three fractions of Z-protein: DE-I, DE-II and DE-III. DE-I is virtually lipid free, DE-II binds palmitic, stearic, oleic, linoleic and arachidonic acids and DE-III binds mainly arachidonic acid.
PtmDeamidation and transpeptidation at the beta carboxyl of Asn- 105 forms an isoaspartyl residue found in an isoform of the DE-III fraction. This rearrangement gives rise to an extra negative charge carried by the acid form
SimilarityBelongs to the calycin superfamily. Fatty-acid binding protein (FABP) family
Subcellular LocationCytoplasm.