LMPD Database

LMP012405

Gene Information

Entrez Gene ID	24404
Gene Name	glutathione peroxidase 1
Gene Symbol	Gpx1
Species	Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0070062	IEA:Ensembl	C	extracellular vesicular exosome
GO:0005739	IEA:Ensembl	C	mitochondrion
GO:0004602	IEA:Ensembl	F	glutathione peroxidase activity
GO:0060055	IEA:Ensembl	P	angiogenesis involved in wound healing
GO:0043534	IEA:Ensembl	P	blood vessel endothelial cell migration
GO:0045454	IEA:Ensembl	P	cell redox homeostasis
GO:0001885	IEA:Ensembl	P	endothelial cell development
GO:0045444	IEA:Ensembl	P	fat cell differentiation
GO:0006749	IEA:Ensembl	P	glutathione metabolic process
GO:0060047	IEA:Ensembl	P	heart contraction
GO:0042744	IEA:Ensembl	P	hydrogen peroxide catabolic process
GO:0051702	IEA:Ensembl	P	interaction with symbiont
GO:0008631	IEA:Ensembl	P	intrinsic apoptotic signaling pathway in response to oxidative stress
GO:0051450	IEA:Ensembl	P	myoblast proliferation
GO:0043066	IEA:Ensembl	P	negative regulation of apoptotic process
GO:0043154	IEA:Ensembl	P	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:1902042	IEA:Ensembl	P	negative regulation of extrinsic apoptotic signaling pathway via death domain receptors
GO:0002862	IEA:Ensembl	P	negative regulation of inflammatory response to antigenic stimulus
GO:1902176	IEA:Ensembl	P	negative regulation of oxidative stress-induced intrinsic apoptotic signaling pathway
GO:0090201	IEA:Ensembl	P	negative regulation of release of cytochrome c from mitochondria
GO:0051897	IEA:Ensembl	P	positive regulation of protein kinase B signaling
GO:0018158	IEA:Ensembl	P	protein oxidation
GO:0040029	IEA:Ensembl	P	regulation of gene expression, epigenetic
GO:0033599	IEA:Ensembl	P	regulation of mammary gland epithelial cell proliferation
GO:0043523	IEA:Ensembl	P	regulation of neuron apoptotic process
GO:0061136	IEA:Ensembl	P	regulation of proteasomal protein catabolic process
GO:0010332	IEA:Ensembl	P	response to gamma radiation
GO:0033194	IEA:Ensembl	P	response to hydroperoxide
GO:0010269	IEA:Ensembl	P	response to selenium ion
GO:0009609	IEA:Ensembl	P	response to symbiotic bacterium
GO:0009636	IEA:Ensembl	P	response to toxic substance
GO:0009410	IEA:Ensembl	P	response to xenobiotic stimulus
GO:0007605	IEA:Ensembl	P	sensory perception of sound
GO:0048741	IEA:Ensembl	P	skeletal muscle fiber development
GO:0043403	IEA:Ensembl	P	skeletal muscle tissue regeneration
GO:0001659	IEA:Ensembl	P	temperature homeostasis
GO:0006641	IEA:Ensembl	P	triglyceride metabolic process
GO:0009650	IEA:Ensembl	P	UV protection
GO:0042311	IEA:Ensembl	P	vasodilation

KEGG Pathway Links

KEGG Pathway ID	Description
ko05014	Amyotrophic lateral sclerosis (ALS)
rno05014	Amyotrophic lateral sclerosis (ALS)
ko00590	Arachidonic acid metabolism
rno00590	Arachidonic acid metabolism
ko00480	Glutathione metabolism
rno00480	Glutathione metabolism
ko05016	Huntington's disease
rno05016	Huntington's disease
ko04918	Thyroid hormone synthesis
rno04918	Thyroid hormone synthesis

REACTOME Pathway Links

REACTOME Pathway ID	Description
5953493	Arachidonic acid metabolism
5953238	Cellular responses to stress
5953323	Detoxification of Reactive Oxygen Species
5953250	Metabolism
5953289	Metabolism of lipids and lipoproteins
5953322	Metabolism of nucleotides
5953320	Purine catabolism
5953321	Purine metabolism
5954556	Synthesis of 12-eicosatetraenoic acid derivatives
5954095	Synthesis of 5-eicosatetraenoic acids