LMPD Database

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LMP012422

Gene Information

Entrez Gene ID24654
Gene Namephospholipase C, beta 1 (phosphoinositide-specific)
Gene SymbolPlcb1
SpeciesRattus norvegicus
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 ISS:BHF-UCLCcytoplasm
GO:0005829 IDA:RGDCcytosol
GO:0016020 IDA:RGDCmembrane
GO:0016607 ISS:BHF-UCLCnuclear speck
GO:0005634 ISS:BHF-UCLCnucleus
GO:0005509 IDA:BHF-UCLFcalcium ion binding
GO:0004435 IDA:RGDFphosphatidylinositol phospholipase C activity
GO:0042803 IDA:RGDFprotein homodimerization activity
GO:0004871 IEA:UniProtKB-KWFsignal transducer activity
GO:0060466 ISS:BHF-UCLPactivation of meiosis involved in egg activation
GO:0021987 ISS:BHF-UCLPcerebral cortex development
GO:0007215 ISS:BHF-UCLPglutamate receptor signaling pathway
GO:0048009 ISS:BHF-UCLPinsulin-like growth factor receptor signaling pathway
GO:0035556 IEA:InterProPintracellular signal transduction
GO:0007612 IEP:RGDPlearning
GO:0016042 IEA:UniProtKB-KWPlipid catabolic process
GO:0007613 IEP:RGDPmemory
GO:2000438 ISS:BHF-UCLPnegative regulation of monocyte extravasation
GO:0045892 ISS:BHF-UCLPnegative regulation of transcription, DNA-templated
GO:0046488 IEP:RGDPphosphatidylinositol metabolic process
GO:2000560 ISS:BHF-UCLPpositive regulation of CD24 biosynthetic process
GO:0048639 ISS:BHF-UCLPpositive regulation of developmental growth
GO:1900087 ISS:BHF-UCLPpositive regulation of G1/S transition of mitotic cell cycle
GO:0032735 ISS:BHF-UCLPpositive regulation of interleukin-12 production
GO:0045663 ISS:BHF-UCLPpositive regulation of myoblast differentiation
GO:0045893 ISS:BHF-UCLPpositive regulation of transcription, DNA-templated
GO:0008277 ISS:BHF-UCLPregulation of G-protein coupled receptor protein signaling pathway
GO:0034284 IDA:BHF-UCLPresponse to monosaccharide
GO:0010243 IEP:RGDPresponse to organonitrogen compound
GO:0043434 IDA:BHF-UCLPresponse to peptide hormone
KEGG Pathway Links
KEGG Pathway IDDescription
ko04261Adrenergic signaling in cardiomyocytes
rno04261Adrenergic signaling in cardiomyocytes
ko05143African trypanosomiasis
rno05143African trypanosomiasis
ko05010Alzheimer's disease
rno05010Alzheimer's disease
ko05146Amoebiasis
rno05146Amoebiasis
ko04020Calcium signaling pathway
rno04020Calcium signaling pathway
ko04022cGMP-PKG signaling pathway
rno04022cGMP-PKG signaling pathway
ko05142Chagas disease (American trypanosomiasis)
rno05142Chagas disease (American trypanosomiasis)
ko04062Chemokine signaling pathway
rno04062Chemokine signaling pathway
rno04725Cholinergic synapse
ko04713Circadian entrainment
rno04713Circadian entrainment
ko04728Dopaminergic synapse
rno04728Dopaminergic synapse
ko04961Endocrine and other factor-regulated calcium reabsorption
rno04961Endocrine and other factor-regulated calcium reabsorption
ko04915Estrogen signaling pathway
rno04915Estrogen signaling pathway
ko04540Gap junction
rno04540Gap junction
ko04971Gastric acid secretion
rno04971Gastric acid secretion
ko04724Glutamatergic synapse
rno04724Glutamatergic synapse
ko04912GnRH signaling pathway
rno04912GnRH signaling pathway
ko05016Huntington's disease
rno05016Huntington's disease
ko04750Inflammatory mediator regulation of TRP channels
rno04750Inflammatory mediator regulation of TRP channels
ko00562Inositol phosphate metabolism
rno00562Inositol phosphate metabolism
M00130Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4
rno04911Insulin secretion
ko04730Long-term depression
rno04730Long-term depression
ko04720Long-term potentiation
rno04720Long-term potentiation
ko04916Melanogenesis
rno04916Melanogenesis
rno01100Metabolic pathways
ko04921Oxytocin signaling pathway
rno04921Oxytocin signaling pathway
ko04972Pancreatic secretion
rno04972Pancreatic secretion
ko04070Phosphatidylinositol signaling system
rno04070Phosphatidylinositol signaling system
rno04611Platelet activation
ko04015Rap1 signaling pathway
rno04015Rap1 signaling pathway
ko04723Retrograde endocannabinoid signaling
rno04723Retrograde endocannabinoid signaling
ko04970Salivary secretion
rno04970Salivary secretion
rno04726Serotonergic synapse
rno04919Thyroid hormone signaling pathway
ko04918Thyroid hormone synthesis
rno04918Thyroid hormone synthesis
ko04270Vascular smooth muscle contraction
rno04270Vascular smooth muscle contraction
ko04310Wnt signaling pathway
rno04310Wnt signaling pathway