LMPD Database

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LMP012446

Gene Information

Entrez Gene ID24890
Gene Nameestrogen receptor 1
Gene SymbolEsr1
SpeciesRattus norvegicus
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:RGDCcytoplasm
GO:0005794 IEA:UniProtKB-KWCGolgi apparatus
GO:0005739 IDA:RGDCmitochondrion
GO:0043005 IDA:RGDCneuron projection
GO:0005634 IDA:UniProtKBCnucleus
GO:0043204 IDA:RGDCperikaryon
GO:0048471 IDA:RGDCperinuclear region of cytoplasm
GO:0005886 IDA:RGDCplasma membrane
GO:0043234 IDA:RGDCprotein complex
GO:0043195 IDA:RGDCterminal bouton
GO:0030315 IDA:RGDCT-tubule
GO:0003682 ISS:UniProtKBFchromatin binding
GO:0001046 IDA:RGDFcore promoter sequence-specific DNA binding
GO:0003677 IMP:RGDFDNA binding
GO:0019899 IPI:RGDFenzyme binding
GO:0030284 IDA:RGDFestrogen receptor activity
GO:0042562 IDA:RGDFhormone binding
GO:0032403 IDA:RGDFprotein complex binding
GO:0003700 IEA:InterProFsequence-specific DNA binding transcription factor activity
GO:0005496 IDA:UniProtKBFsteroid binding
GO:0003707 IDA:RGDFsteroid hormone receptor activity
GO:0031798 IPI:RGDFtype 1 metabotropic glutamate receptor binding
GO:0008270 IEA:InterProFzinc ion binding
GO:1990375 IEP:RGDPbaculum development
GO:0071392 IDA:UniProtKBPcellular response to estradiol stimulus
GO:0046697 IEP:RGDPdecidualization
GO:0030518 IDA:UniProtKBPintracellular steroid hormone receptor signaling pathway
GO:0008584 IEP:RGDPmale gonad development
GO:0046325 IDA:RGDPnegative regulation of glucose import
GO:0043124 ISS:UniProtKBPnegative regulation of I-kappaB kinase/NF-kappaB signaling
GO:1901215 IDA:RGDPnegative regulation of neuron death
GO:0043433 ISS:UniProtKBPnegative regulation of sequence-specific DNA binding transcription factor activity
GO:0048662 IMP:RGDPnegative regulation of smooth muscle cell proliferation
GO:0090209 IDA:RGDPnegative regulation of triglyceride metabolic process
GO:0002076 IEP:RGDPosteoblast development
GO:0007200 IDA:UniProtKBPphospholipase C-activating G-protein coupled receptor signaling pathway
GO:0007204 IDA:UniProtKBPpositive regulation of cytosolic calcium ion concentration
GO:0045742 IMP:RGDPpositive regulation of epidermal growth factor receptor signaling pathway
GO:0070374 IDA:RGDPpositive regulation of ERK1 and ERK2 cascade
GO:0045429 ISS:UniProtKBPpositive regulation of nitric oxide biosynthetic process
GO:0051000 ISS:UniProtKBPpositive regulation of nitric-oxide synthase activity
GO:0010863 IDA:UniProtKBPpositive regulation of phospholipase C activity
GO:0051091 ISS:UniProtKBPpositive regulation of sequence-specific DNA binding transcription factor activity
GO:0045944 TAS:RGDPpositive regulation of transcription from RNA polymerase II promoter
GO:0043523 IDA:RGDPregulation of neuron apoptotic process
GO:0032355 IEP:RGDPresponse to estradiol
GO:0060009 IEP:RGDPSertoli cell development
GO:0060011 IMP:RGDPSertoli cell proliferation
GO:0006351 IEA:UniProtKB-KWPtranscription, DNA-templated
KEGG Pathway Links
KEGG Pathway IDDescription
ko04961Endocrine and other factor-regulated calcium reabsorption
rno04961Endocrine and other factor-regulated calcium reabsorption
ko04915Estrogen signaling pathway
rno04915Estrogen signaling pathway
ko04917Prolactin signaling pathway
rno04917Prolactin signaling pathway
ko05205Proteoglycans in cancer
rno05205Proteoglycans in cancer
rno04919Thyroid hormone signaling pathway
REACTOME Pathway Links
REACTOME Pathway IDDescription
5953330Gene Expression
5953833Generic Transcription Pathway
5954147Nuclear Receptor transcription pathway
5954400Nuclear signaling by ERBB4
5953540Signaling by ERBB4
5953381Signal Transduction