LMPD Database

LMP012489

Record overview

LMPD ID	LMP012489
Gene ID	25277
Species	Macaca mulata (Rhesus monkey)
Gene Name	milk fat globule-EGF factor 8 protein
Gene Symbol	Mfge8
Synonyms	AGS; MFGME8; OAcGD3S; MFGMP-E8;
Alternate names	lactadherin; MFGM; SED1; MFG-E8; O-acetyl GD3 ganglioside synthase; O-acetyl disialoganglioside synthase; O-acetyltransferase milk fat globule membrane protein; O-acetyltransferase Milk fat glolbule membrane protein;
Chromosome	1
Map Location	1q31
Summary	involved in the O-acetylation of GD3 ganglioside sialic acid [RGD, Feb 2006]
Orthologs	View orthologs and multiple alignments for Mfge8

Proteins

lactadherin isoform 1 precursor

Refseq ID:	NP_001035276
Protein GI:	93277126
UniProt ID:	Q1PBJ1
mRNA ID:	NM_001040186
Length:	483
RefSeq Status:

MQFSRVLAALCGVLLCASGLFAASGDFCDSSLCLNGGTCLMGQDNDIYCLCPEGFTGLVCNETEKGPCSPNPCFHDAKCLVTEDTQRGDIFTEYICQCPV
GYSGIHCELETTSYLDGEYLSSPAVPTTAVPTTAIPTTAVPTTAVPTTAVPTPAPNPDLSNHLASRCSTKLGLEGGAIADSQISASSVYMGFMGLQRWGP
ELARLYRTGIVNAWTASSYDSKPWIQVDFLRKMRVSGVMTQGASRAGRAEYLKTFKVAYSLDGRRFEFIQDESGTGDKEFMGNQDNNSLKINMFNPTLEA
QYIRLYPVSCHRGCTLRFELLGCELHGCSEPLGLKNNTIPDSQITASSSYKTWNLRAFGWYPHLGRLDNQGKINAWTAQSNSAKEWLQVDLGTQKKVTGI
ITQGARDFGHIQYVASYKVAHSDDGVQWTVYEEQGTSKVFQGNLDNNSHKKNIFEKPFMARYVRVLPLSWHNRITLRLELLGC


sig_peptide: 1..22
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2271
peptide sequence: 
MQFSRVLAALCGVLLCASGLFA

mat_peptide: 23..483
product: lactadherin isoform 1
calculated_mol_wt: 50848
peptide sequence: 
ASGDFCDSSLCLNGGTCLMGQDNDIYCLCPEGFTGLVCNETEKGPCSPNPCFHDAKCLVTEDTQRGDIFTEYICQCPVGYSGIHCELETTSYLDGEYLSS
PAVPTTAVPTTAIPTTAVPTTAVPTTAVPTPAPNPDLSNHLASRCSTKLGLEGGAIADSQISASSVYMGFMGLQRWGPELARLYRTGIVNAWTASSYDSK
PWIQVDFLRKMRVSGVMTQGASRAGRAEYLKTFKVAYSLDGRRFEFIQDESGTGDKEFMGNQDNNSLKINMFNPTLEAQYIRLYPVSCHRGCTLRFELLG
CELHGCSEPLGLKNNTIPDSQITASSSYKTWNLRAFGWYPHLGRLDNQGKINAWTAQSNSAKEWLQVDLGTQKKVTGIITQGARDFGHIQYVASYKVAHS
DDGVQWTVYEEQGTSKVFQGNLDNNSHKKNIFEKPFMARYVRVLPLSWHNRITLRLELLGC

lactadherin isoform 2 precursor

Refseq ID:	NP_036943
Protein GI:	6981200
UniProt ID:	P70490
mRNA ID:	NM_012811
Length:	427
RefSeq Status:

MQFSRVLAALCGVLLCASGLFAASGDFCDSSLCLNGGTCLMGQDNDIYCLCPEGFTGLVCNETEKGPCSPNPCFHDAKCLVTEDTQRGDIFTEYICQCPV
GYSGIHCELGCSTKLGLEGGAIADSQISASSVYMGFMGLQRWGPELARLYRTGIVNAWTASSYDSKPWIQVDFLRKMRVSGVMTQGASRAGRAEYLKTFK
VAYSLDGRRFEFIQDESGTGDKEFMGNQDNNSLKINMFNPTLEAQYIRLYPVSCHRGCTLRFELLGCELHGCSEPLGLKNNTIPDSQITASSSYKTWNLR
AFGWYPHLGRLDNQGKINAWTAQSNSAKEWLQVDLGTQKKVTGIITQGARDFGHIQYVASYKVAHSDDGVQWTVYEEQGTSKVFQGNLDNNSHKKNIFEK
PFMARYVRVLPLSWHNRITLRLELLGC


sig_peptide: 1..22
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2271
peptide sequence: 
MQFSRVLAALCGVLLCASGLFA

mat_peptide: 23..483
product: lactadherin isoform 1
calculated_mol_wt: 50848
peptide sequence: 
ASGDFCDSSLCLNGGTCLMGQDNDIYCLCPEGFTGLVCNETEKGPCSPNPCFHDAKCLVTEDTQRGDIFTEYICQCPVGYSGIHCELETTSYLDGEYLSS
PAVPTTAVPTTAIPTTAVPTTAVPTTAVPTPAPNPDLSNHLASRCSTKLGLEGGAIADSQISASSVYMGFMGLQRWGPELARLYRTGIVNAWTASSYDSK
PWIQVDFLRKMRVSGVMTQGASRAGRAEYLKTFKVAYSLDGRRFEFIQDESGTGDKEFMGNQDNNSLKINMFNPTLEAQYIRLYPVSCHRGCTLRFELLG
CELHGCSEPLGLKNNTIPDSQITASSSYKTWNLRAFGWYPHLGRLDNQGKINAWTAQSNSAKEWLQVDLGTQKKVTGIITQGARDFGHIQYVASYKVAHS
DDGVQWTVYEEQGTSKVFQGNLDNNSHKKNIFEKPFMARYVRVLPLSWHNRITLRLELLGC

sig_peptide: 1..22
inference: COORDINATES: ab initio prediction:SignalP:4.0
calculated_mol_wt: 2271
peptide sequence: 
MQFSRVLAALCGVLLCASGLFA

mat_peptide: 23..427
product: Lactadherin
experiment: experimental evidence, no additional details recorded
note: propagated from UniProtKB/Swiss-Prot (P70490.1)
calculated_mol_wt: 45160
peptide sequence: 
ASGDFCDSSLCLNGGTCLMGQDNDIYCLCPEGFTGLVCNETEKGPCSPNPCFHDAKCLVTEDTQRGDIFTEYICQCPVGYSGIHCELGCSTKLGLEGGAI
ADSQISASSVYMGFMGLQRWGPELARLYRTGIVNAWTASSYDSKPWIQVDFLRKMRVSGVMTQGASRAGRAEYLKTFKVAYSLDGRRFEFIQDESGTGDK
EFMGNQDNNSLKINMFNPTLEAQYIRLYPVSCHRGCTLRFELLGCELHGCSEPLGLKNNTIPDSQITASSSYKTWNLRAFGWYPHLGRLDNQGKINAWTA
QSNSAKEWLQVDLGTQKKVTGIITQGARDFGHIQYVASYKVAHSDDGVQWTVYEEQGTSKVFQGNLDNNSHKKNIFEKPFMARYVRVLPLSWHNRITLRL
ELLGC