LMPD Database

LMP012499

UniProt Annotations

Entry Information
Gene Namehydroxysteroid (17-beta) dehydrogenase 1
Protein EntryDHB1_RAT
UniProt IDP51657
SpeciesRat
Comments
Comment typeDescription
Catalytic Activity17-beta-estradiol + NAD(P)(+) = estrone + NAD(P)H
FunctionFavors the reduction of estrogens and androgens. Uses preferentially NADH.
PathwaySteroid biosynthesis; estrogen biosynthesis.
SimilarityBelongs to the short-chain dehydrogenases/reductases (SDR) family
Subcellular LocationCytoplasm.
SubunitHomodimer