LMPD Database

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LMP012533

UniProt Annotations

Entry Information
Gene Namefatty acid binding protein 2, intestinal
Protein EntryFABPI_RAT
UniProt IDP02693
SpeciesRat
Comments
Comment typeDescription
DomainForms a beta-barrel structure that accommodates the hydrophobic ligand in its interior.
FunctionFABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long- chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor (By similarity)
InductionBy peptide YY
SimilarityBelongs to the calycin superfamily. Fatty-acid binding protein (FABP) family
Subcellular LocationCytoplasm.
Tissue SpecificityExpressed in the small intestine. Expression in the mucosal cells of the ileum extends from the midvillar region to the villus tips