LMPD Database

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LMP012546

UniProt Annotations

Entry Information
Gene Namecolipase, pancreatic
Protein EntryCOL_RAT
UniProt IDP17084
SpeciesRat
Comments
Comment typeDescription
FunctionColipase is a cofactor of pancreatic lipase. It allows the lipase to anchor itself to the lipid-water interface. Without colipase the enzyme is washed off by bile salts, which have an inhibitory effect on the lipase.
FunctionEnterostatin has a biological activity as a satiety signal
SimilarityBelongs to the colipase family. {ECO:0000255|PROSITE- ProRule:PRU00674}.
Subcellular LocationSecreted.
SubunitForms a 1:1 stoichiometric complex with pancreatic lipase
Tissue SpecificityExpressed by the pancreas.