LMPD Database

LMP012547

Gene Information

Entrez Gene ID	25682
Gene Name	peroxisome proliferator-activated receptor delta
Gene Symbol	Ppard
Species	Rattus norvegicus

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005634	IDA:RGD	C	nucleus
GO:0008144	IEA:Ensembl	F	drug binding
GO:0005504	IDA:RGD	F	fatty acid binding
GO:0004879	TAS:RGD	F	ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity
GO:0070539	IEA:Ensembl	F	linoleic acid binding
GO:0051059	IPI:RGD	F	NF-kappaB binding
GO:0043565	IEA:InterPro	F	sequence-specific DNA binding
GO:0003700	TAS:RGD	F	sequence-specific DNA binding transcription factor activity
GO:0003707	IEA:InterPro	F	steroid hormone receptor activity
GO:0003713	IDA:RGD	F	transcription coactivator activity
GO:0008270	IEA:InterPro	F	zinc ion binding
GO:0060612	IEA:Ensembl	P	adipose tissue development
GO:0097190	IEA:Ensembl	P	apoptotic signaling pathway
GO:0008366	IEA:Ensembl	P	axon ensheathment
GO:0030154	IEA:Ensembl	P	cell differentiation
GO:0031589	IEA:Ensembl	P	cell-substrate adhesion
GO:0071456	IEA:Ensembl	P	cellular response to hypoxia
GO:0046697	IEP:RGD	P	decidualization
GO:0007566	IEP:RGD	P	embryo implantation
GO:0006635	IEA:Ensembl	P	fatty acid beta-oxidation
GO:0019395	IDA:RGD	P	fatty acid oxidation
GO:0015908	IEA:Ensembl	P	fatty acid transport
GO:0007507	IEP:RGD	P	heart development
GO:0030522	TAS:GOC	P	intracellular receptor signaling pathway
GO:0051546	IEA:Ensembl	P	keratinocyte migration
GO:0043616	IEA:Ensembl	P	keratinocyte proliferation
GO:0006629	IDA:RGD	P	lipid metabolic process
GO:0009299	IDA:RGD	P	mRNA transcription
GO:0043066	IDA:RGD	P	negative regulation of apoptotic process
GO:0030308	IDA:RGD	P	negative regulation of cell growth
GO:0032966	IMP:RGD	P	negative regulation of collagen biosynthetic process
GO:0050680	IEA:Ensembl	P	negative regulation of epithelial cell proliferation
GO:0050728	IDA:RGD	P	negative regulation of inflammatory response
GO:0014912	IDA:RGD	P	negative regulation of smooth muscle cell migration
GO:0048662	IDA:RGD	P	negative regulation of smooth muscle cell proliferation
GO:0000122	IEA:Ensembl	P	negative regulation of transcription from RNA polymerase II promoter
GO:0008654	IDA:RGD	P	phospholipid biosynthetic process
GO:0008284	IEA:Ensembl	P	positive regulation of cell proliferation
GO:0045684	IDA:RGD	P	positive regulation of epidermis development
GO:0032024	IDA:RGD	P	positive regulation of insulin secretion
GO:0014068	IEA:Ensembl	P	positive regulation of phosphatidylinositol 3-kinase signaling
GO:0045893	IEA:Ensembl	P	positive regulation of transcription, DNA-templated
GO:0045909	IDA:RGD	P	positive regulation of vasodilation
GO:0006029	IDA:RGD	P	proteoglycan metabolic process
GO:0045598	IEA:Ensembl	P	regulation of fat cell differentiation
GO:0014823	IEP:RGD	P	response to activity
GO:0009749	IEP:RGD	P	response to glucose
GO:0010033	IEP:RGD	P	response to organic substance
GO:0033189	IEP:RGD	P	response to vitamin A
GO:0006776	IMP:RGD	P	vitamin A metabolic process
GO:0042060	IEA:Ensembl	P	wound healing

KEGG Pathway Links

KEGG Pathway ID	Description
ko05221	Acute myeloid leukemia
rno05221	Acute myeloid leukemia
rno05200	Pathways in cancer
ko03320	PPAR signaling pathway
rno03320	PPAR signaling pathway
ko04310	Wnt signaling pathway
rno04310	Wnt signaling pathway

REACTOME Pathway Links

REACTOME Pathway ID	Description
5953288	Fatty acid, triacylglycerol, and ketone body metabolism
5953330	Gene Expression
5953833	Generic Transcription Pathway
5953467	Import of palmitoyl-CoA into the mitochondrial matrix
5953250	Metabolism
5953289	Metabolism of lipids and lipoproteins
5954147	Nuclear Receptor transcription pathway
5953268	Pyruvate metabolism
5953269	Pyruvate metabolism and Citric Acid (TCA) cycle
5954047	Regulation of pyruvate dehydrogenase (PDH) complex
5953270	The citric acid (TCA) cycle and respiratory electron transport