LMPD Database

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LMP012574

Gene Information

Entrez Gene ID29260
Gene Nametoll-like receptor 4
Gene SymbolTlr4
SpeciesRattus norvegicus
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0009986 IDA:RGDCcell surface
GO:0005737 IDA:RGDCcytoplasm
GO:0005887 TAS:RGDCintegral component of plasma membrane
GO:0046696 ISS:UniProtKBClipopolysaccharide receptor complex
GO:0001530 IDA:RGDFlipopolysaccharide binding
GO:0001875 ISS:UniProtKBFlipopolysaccharide receptor activity
GO:0043548 IPI:RGDFphosphatidylinositol 3-kinase binding
GO:0004872 IDA:RGDFreceptor activity
GO:0004888 IEA:InterProFtransmembrane signaling receptor activity
GO:0071222 IEP:RGDPcellular response to lipopolysaccharide
GO:0071260 IEP:RGDPcellular response to mechanical stimulus
GO:0071300 IEP:RGDPcellular response to retinoic acid
GO:0050829 IEA:InterProPdefense response to Gram-negative bacterium
GO:0032497 ISS:UniProtKBPdetection of lipopolysaccharide
GO:0016064 IEP:RGDPimmunoglobulin mediated immune response
GO:0006954 IEP:RGDPinflammatory response
GO:0045087 TAS:RGDPinnate immune response
GO:0002758 IMP:RGDPinnate immune response-activating signal transduction
GO:0006691 IDA:RGDPleukotriene metabolic process
GO:0001774 IDA:RGDPmicroglial cell activation
GO:0002755 IEA:InterProPMyD88-dependent toll-like receptor signaling pathway
GO:0043065 IMP:RGDPpositive regulation of apoptotic process
GO:0043388 IMP:RGDPpositive regulation of DNA binding
GO:0050729 IMP:RGDPpositive regulation of inflammatory response
GO:0051092 IMP:RGDPpositive regulation of NF-kappaB transcription factor activity
GO:0050731 IDA:RGDPpositive regulation of peptidyl-tyrosine phosphorylation
GO:0051091 IMP:RGDPpositive regulation of sequence-specific DNA binding transcription factor activity
GO:0050707 IEA:InterProPregulation of cytokine secretion
GO:0051930 IMP:RGDPregulation of sensory perception of pain
GO:0014823 IEP:RGDPresponse to activity
GO:0045471 IMP:RGDPresponse to ethanol
GO:0070542 IDA:RGDPresponse to fatty acid
GO:0051384 IEP:RGDPresponse to glucocorticoid
GO:1990268 IEP:RGDPresponse to gold nanoparticle
GO:0001666 IEP:RGDPresponse to hypoxia
GO:0032868 IEP:RGDPresponse to insulin
GO:0032496 IDA:RGDPresponse to lipopolysaccharide
GO:0043278 IEP:RGDPresponse to morphine
GO:0006979 IMP:RGDPresponse to oxidative stress
GO:0032570 IEP:RGDPresponse to progesterone
GO:0032526 IEP:RGDPresponse to retinoic acid
GO:0009636 IEP:RGDPresponse to toxic substance
GO:0003009 IEP:RGDPskeletal muscle contraction
GO:0034142 IEA:InterProPtoll-like receptor 4 signaling pathway
GO:0002224 IDA:RGDPtoll-like receptor signaling pathway
KEGG Pathway Links
KEGG Pathway IDDescription
ko05146Amoebiasis
rno05146Amoebiasis
ko05142Chagas disease (American trypanosomiasis)
rno05142Chagas disease (American trypanosomiasis)
rno05161Hepatitis B
rno04066HIF-1 signaling pathway
ko05321Inflammatory bowel disease (IBD)
rno05321Inflammatory bowel disease (IBD)
ko05164Influenza A
rno05164Influenza A
ko05134Legionellosis
rno05134Legionellosis
ko05140Leishmaniasis
rno05140Leishmaniasis
ko05144Malaria
rno05144Malaria
ko05162Measles
rno05162Measles
rno04064NF-kappa B signaling pathway
ko05133Pertussis
rno05133Pertussis
ko04145Phagosome
rno04145Phagosome
ko04151PI3K-Akt signaling pathway
rno04151PI3K-Akt signaling pathway
ko05205Proteoglycans in cancer
rno05205Proteoglycans in cancer
ko05323Rheumatoid arthritis
rno05323Rheumatoid arthritis
ko05132Salmonella infection
rno05132Salmonella infection
ko04620Toll-like receptor signaling pathway
rno04620Toll-like receptor signaling pathway
ko05145Toxoplasmosis
rno05145Toxoplasmosis
ko05152Tuberculosis
rno05152Tuberculosis