LMPD Database

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LMP012589

UniProt Annotations

Entry Information
Gene Namepalmitoyl-protein thioesterase 1
Protein EntryPPT1_RAT
UniProt IDP45479
SpeciesRat
Comments
Comment typeDescription
Catalytic ActivityPalmitoyl-[protein] + H(2)O = palmitate + [protein].
FunctionRemoves thioester-linked fatty acyl groups such as palmitate from modified cysteine residues in proteins or peptides during lysosomal degradation. Prefers acyl chain lengths of 14 to 18 carbons.
SimilarityBelongs to the palmitoyl-protein thioesterase family
Subcellular LocationLysosome.
Tissue SpecificityHighest amounts in brain, testis, lung, and spleen. Lowest amounts in liver and skeletal muscle.