LMPD Database

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LMP012619

Gene Information

Entrez Gene ID29637
Gene Name3-hydroxy-3-methylglutaryl-CoA synthase 1 (soluble)
Gene SymbolHmgcs1
SpeciesRattus norvegicus
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005829 IDA:RGDCcytosol
GO:0005634 IEA:EnsemblCnucleus
GO:0005886 IEA:EnsemblCplasma membrane
GO:0008144 IDA:RGDFdrug binding
GO:0004421 IDA:RGDFhydroxymethylglutaryl-CoA synthase activity
GO:0016853 IDA:RGDFisomerase activity
GO:0043177 IDA:RGDForganic acid binding
GO:0042803 IDA:RGDFprotein homodimerization activity
GO:0007420 IEP:RGDPbrain development
GO:0071397 IEP:RGDPcellular response to cholesterol
GO:0071372 IEP:RGDPcellular response to follicle-stimulating hormone stimulus
GO:0071407 IEP:RGDPcellular response to organic cyclic compound
GO:0006695 IEA:UniProtKB-KWPcholesterol biosynthetic process
GO:0008299 IEA:InterProPisoprenoid biosynthetic process
GO:0001889 IEP:RGDPliver development
GO:0008584 IEP:RGDPmale gonad development
GO:0070723 IEP:RGDPresponse to cholesterol
GO:0042493 IEP:RGDPresponse to drug
GO:0034698 IEP:RGDPresponse to gonadotropin
GO:0009725 IEP:RGDPresponse to hormone
GO:0055094 IEP:RGDPresponse to lipoprotein particle
GO:0009645 IEP:RGDPresponse to low light intensity stimulus
GO:0014070 IEP:RGDPresponse to organic cyclic compound
GO:0010033 IEP:RGDPresponse to organic substance
GO:0010243 IDA:RGDPresponse to organonitrogen compound
GO:0014074 IEP:RGDPresponse to purine-containing compound
GO:0046690 IEP:RGDPresponse to tellurium ion
GO:0033197 IEP:RGDPresponse to vitamin E
KEGG Pathway Links
KEGG Pathway IDDescription
ko00650Butanoate metabolism
rno00650Butanoate metabolism
M00095C5 isoprenoid biosynthesis, mevalonate pathway
rno01100Metabolic pathways
ko00072Synthesis and degradation of ketone bodies
rno00072Synthesis and degradation of ketone bodies
ko00900Terpenoid backbone biosynthesis
rno00900Terpenoid backbone biosynthesis
ko00280Valine, leucine and isoleucine degradation
rno00280Valine, leucine and isoleucine degradation
REACTOME Pathway Links
REACTOME Pathway IDDescription
5954496Activation of gene expression by SREBF (SREBP)
5953924Cholesterol biosynthesis
5953288Fatty acid, triacylglycerol, and ketone body metabolism
5953250Metabolism
5953289Metabolism of lipids and lipoproteins
5954333PPARA activates gene expression
5954497Regulation of cholesterol biosynthesis by SREBP (SREBF)
5954222Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)