LMPD Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
LMP012664

UniProt Annotations

Entry Information
Gene Nameplatelet-activating factor receptor
Protein EntryPTAFR_RAT
UniProt IDP46002
SpeciesRat
Comments
Comment typeDescription
FunctionReceptor for platelet activating factor, a chemotactic phospholipid mediator that possesses potent inflammatory, smooth- muscle contractile and hypotensive activity. Seems to mediate its action via a G protein that activates a phosphatidylinositol- calcium second messenger system.
SimilarityBelongs to the G-protein coupled receptor 1 family
Subcellular LocationCell membrane; Multi-pass membrane protein.
SubunitInteracts with ARRB1
Tissue SpecificityPresent in almost all organs including spleen, small intestine, kidney, lung, liver and brain.