LMPD Database

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LMP012672

UniProt Annotations

Entry Information
Gene Nameinositol hexakisphosphate kinase 2
Protein EntryIP6K2_RAT
UniProt IDQ9R0U1
SpeciesRat
Comments
Comment typeDescription
Catalytic ActivityATP + 1D-myo-inositol 1-diphosphate 2,3,4,5,6- pentakisphosphate = ADP + 1D-myo-inositol 1,5-bis(diphosphate) 2,3,4,6-tetrakisphosphate.
Catalytic ActivityATP + 1D-myo-inositol hexakisphosphate = ADP + 1D-myo-inositol 5-diphosphate 1,2,3,4,6-pentakisphosphate.
FunctionConverts inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). Converts 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4 (By similarity). Was first identified because of its ability to stimulate Na(+)- dependent phosphate cotransport. {ECO:0000250, ECO:0000269|PubMed:10527952}.
Sequence CautionSequence=BAA87611.1; Type=Miscellaneous discrepancy; Note=Chimeric cDNA.; Evidence= ;
SimilarityBelongs to the inositol phosphokinase (IPK) family
Subcellular LocationNucleus .
Tissue SpecificityHighly expressed in small intestine