LMPD Database

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LMP012849

UniProt Annotations

Entry Information
Gene Namenuclear receptor subfamily 2, group F, member 2
Protein EntryCOT2_RAT
UniProt IDO09018
SpeciesRat
Comments
Comment typeDescription
FunctionLigand-activated transcription factor. Activated by high concentrations of 9-cis-retinoic acid and all-trans-retinoic acid, but not by dexamethasone, cortisol or progesterone (in vitro). Regulation of the apolipoprotein A-I gene transcription. Binds to DNA site A (By similarity)
SimilarityBelongs to the nuclear hormone receptor family. NR2 subfamily
SimilarityContains 1 nuclear receptor DNA-binding domain
Subcellular LocationNucleus.
SubunitInteracts with SQSTM1. Binds DNA as a dimer; homodimer or heterodimer with NR2F6. Interacts with NCOA1, NCOA2, NCOA3 and PPARGC1A. Interacts with ZFPM2 (By similarity)