LMPD Database

LMP012853

UniProt Annotations

Entry Information
Gene Nameleukotriene C4 synthase
Protein EntryLTC4S_RAT
UniProt IDQ925U2
SpeciesRat
Comments
Comment typeDescription
Catalytic ActivityLeukotriene C(4) = leukotriene A(4) + glutathione.
FunctionCatalyzes the conjugation of leukotriene A4 with reduced glutathione to form leukotriene C4
InductionUp-regulated by all-trans retinoic acid
SimilarityBelongs to the MAPEG family
Subcellular LocationNucleus outer membrane ; Multi- pass membrane protein . Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein .
SubunitHomotrimer. Interacts with ALOX5AP and ALOX5 (By similarity)