LMPD Database

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LMP012861

UniProt Annotations

Entry Information
Gene Namephytanoyl-CoA 2-hydroxylase
Protein EntryPAHX_RAT
UniProt IDP57093
SpeciesRat
Comments
Comment typeDescription
Catalytic ActivityPhytanoyl-CoA + 2-oxoglutarate + O(2) = 2- hydroxyphytanoyl-CoA + succinate + CO(2).
CofactorName=Fe cation; Xref=ChEBI:CHEBI:24875;
CofactorName=L-ascorbate; Xref=ChEBI:CHEBI:38290;
FunctionConverts phytanoyl-CoA to 2-hydroxyphytanoyl-CoA.
PathwayLipid metabolism; fatty acid metabolism.
SimilarityBelongs to the PhyH family
Subcellular LocationPeroxisome.
SubunitInteracts specifically with the immunophilin FKBP52 and PHYHIP