LMPD Database

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LMP012891

UniProt Annotations

Entry Information
Gene Namehydroxysteroid (17-beta) dehydrogenase 3
Protein EntryDHB3_RAT
UniProt IDO54939
SpeciesRat
Comments
Comment typeDescription
Catalytic ActivityTestosterone + NADP(+) = androst-4-ene-3,17- dione + NADPH.
FunctionFavors the reduction of androstenedione to testosterone. Uses NADPH while the two other EDH17B enzymes use NADH (By similarity)
PathwayHormone biosynthesis; testosterone biosynthesis.
SimilarityBelongs to the short-chain dehydrogenases/reductases (SDR) family. 17-beta-HSD 3 subfamily