LMPD Database

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LMP012895

UniProt Annotations

Entry Information
Gene Nameemopamil binding protein (sterol isomerase)
Protein EntryEBP_RAT
UniProt IDQ9JJ46
SpeciesRat
Comments
Comment typeDescription
Catalytic Activity5-alpha-cholest-7-en-3-beta-ol = 5-alpha- cholest-8-en-3-beta-ol.
FunctionCatalyzes the conversion of Delta(8)-sterols to their corresponding Delta(7)-isomers
MiscellaneousBinds to the phenylalkylamine calcium-ion antagonist emopamil, an anti-ischemic drug.
PathwaySteroid biosynthesis; cholesterol biosynthesis.
SimilarityBelongs to the EBP family
Subcellular LocationEndoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein .