LMPD Database

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LMP012935

Gene Information

Entrez Gene ID171104
Gene NameG protein-coupled estrogen receptor 1
Gene SymbolGper1
SpeciesRattus norvegicus
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0030424 IDA:UniProtKBCaxon
GO:0043679 IDA:UniProtKBCaxon terminus
GO:0030054 IEA:UniProtKB-KWCcell junction
GO:0005737 IDA:UniProtKBCcytoplasm
GO:0030659 ISS:UniProtKBCcytoplasmic vesicle membrane
GO:0030425 IDA:UniProtKBCdendrite
GO:0043198 IDA:UniProtKBCdendritic shaft
GO:0044327 IDA:UniProtKBCdendritic spine head
GO:0032591 IDA:UniProtKBCdendritic spine membrane
GO:0005769 ISS:UniProtKBCearly endosome
GO:0005783 ISS:UniProtKBCendoplasmic reticulum
GO:0005794 IDA:UniProtKBCGolgi apparatus
GO:0016021 IEA:UniProtKB-KWCintegral component of membrane
GO:0005622 ISS:UniProtKBCintracellular
GO:0045095 ISS:UniProtKBCkeratin filament
GO:0031966 IDA:UniProtKBCmitochondrial membrane
GO:0097481 IDA:UniProtKBCneuronal postsynaptic density
GO:0005635 ISS:UniProtKBCnuclear envelope
GO:0005634 ISS:UniProtKBCnucleus
GO:0048471 ISS:UniProtKBCperinuclear region of cytoplasm
GO:0005886 IDA:UniProtKBCplasma membrane
GO:0014069 IDA:UniProtKBCpostsynaptic density
GO:0045211 IEA:UniProtKB-KWCpostsynaptic membrane
GO:0048786 IDA:UniProtKBCpresynaptic active zone
GO:0042734 IDA:UniProtKBCpresynaptic membrane
GO:0055037 ISS:UniProtKBCrecycling endosome
GO:0005802 ISS:UniProtKBCtrans-Golgi network
GO:0008144 IDA:RGDFdrug binding
GO:0030284 IDA:UniProtKBFestrogen receptor activity
GO:0004930 IEA:UniProtKB-KWFG-protein coupled receptor activity
GO:0042562 IDA:RGDFhormone binding
GO:0017082 IDA:UniProtKBFmineralocorticoid receptor activity
GO:0005496 IDA:RGDFsteroid binding
GO:0003707 IDA:RGDFsteroid hormone receptor activity
GO:0030263 IDA:UniProtKBPapoptotic chromosome condensation
GO:0007049 IEA:UniProtKB-KWPcell cycle
GO:0071392 IDA:UniProtKBPcellular response to estradiol stimulus
GO:0071333 ISS:UniProtKBPcellular response to glucose stimulus
GO:0071389 IDA:UniProtKBPcellular response to mineralocorticoid stimulus
GO:0071375 ISS:UniProtKBPcellular response to peptide hormone stimulus
GO:0071356 ISS:UniProtKBPcellular response to tumor necrosis factor
GO:0051480 ISS:UniProtKBPcytosolic calcium ion homeostasis
GO:0006954 IEA:UniProtKB-KWPinflammatory response
GO:0045087 IEA:UniProtKB-KWPinnate immune response
GO:0030518 IDA:RGDPintracellular steroid hormone receptor signaling pathway
GO:0031959 IDA:GOCPmineralocorticoid receptor signaling pathway
GO:0071157 ISS:UniProtKBPnegative regulation of cell cycle arrest
GO:0008285 IDA:UniProtKBPnegative regulation of cell proliferation
GO:0051053 IDA:UniProtKBPnegative regulation of DNA metabolic process
GO:0045599 ISS:UniProtKBPnegative regulation of fat cell differentiation
GO:0010629 IDA:UniProtKBPnegative regulation of gene expression
GO:0050728 ISS:UniProtKBPnegative regulation of inflammatory response
GO:0002695 ISS:UniProtKBPnegative regulation of leukocyte activation
GO:0051055 ISS:UniProtKBPnegative regulation of lipid biosynthetic process
GO:0019228 ISS:UniProtKBPneuronal action potential
GO:0030264 IDA:UniProtKBPnuclear fragmentation involved in apoptotic nuclear change
GO:0010579 ISS:UniProtKBPpositive regulation of adenylate cyclase activity involved in G-protein coupled receptor signaling pathway
GO:0043065 IDA:UniProtKBPpositive regulation of apoptotic process
GO:0030819 ISS:UniProtKBPpositive regulation of cAMP biosynthetic process
GO:0030335 ISS:UniProtKBPpositive regulation of cell migration
GO:0008284 ISS:UniProtKBPpositive regulation of cell proliferation
GO:0043280 IDA:UniProtKBPpositive regulation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007204 ISS:UniProtKBPpositive regulation of cytosolic calcium ion concentration
GO:2000353 IDA:UniProtKBPpositive regulation of endothelial cell apoptotic process
GO:0045742 IMP:RGDPpositive regulation of epidermal growth factor receptor signaling pathway
GO:0070374 IDA:UniProtKBPpositive regulation of ERK1 and ERK2 cascade
GO:0090004 ISS:UniProtKBPpositive regulation of establishment of protein localization to plasma membrane
GO:2001238 IDA:UniProtKBPpositive regulation of extrinsic apoptotic signaling pathway
GO:0010628 IDA:UniProtKBPpositive regulation of gene expression
GO:0045745 ISS:UniProtKBPpositive regulation of G-protein coupled receptor protein signaling pathway
GO:0032962 ISS:UniProtKBPpositive regulation of inositol trisphosphate biosynthetic process
GO:0032024 ISS:UniProtKBPpositive regulation of insulin secretion
GO:0043410 ISS:UniProtKBPpositive regulation of MAPK cascade
GO:0050769 ISS:UniProtKBPpositive regulation of neurogenesis
GO:0001956 ISS:UniProtKBPpositive regulation of neurotransmitter secretion
GO:0014068 IDA:RGDPpositive regulation of phosphatidylinositol 3-kinase signaling
GO:0001934 IDA:UniProtKBPpositive regulation of protein phosphorylation
GO:0090200 IDA:UniProtKBPpositive regulation of release of cytochrome c from mitochondria
GO:0051281 ISS:UniProtKBPpositive regulation of release of sequestered calcium ion into cytosol
GO:0045944 ISS:UniProtKBPpositive regulation of transcription from RNA polymerase II promoter
GO:0070474 ISS:UniProtKBPpositive regulation of uterine smooth muscle contraction
GO:0045909 IDA:UniProtKBPpositive regulation of vasodilation
GO:0043401 IDA:GOCPsteroid hormone mediated signaling pathway
KEGG Pathway Links
KEGG Pathway IDDescription
ko04915Estrogen signaling pathway
rno04915Estrogen signaling pathway
REACTOME Pathway Links
REACTOME Pathway IDDescription
5954122Class A/1 (Rhodopsin-like receptors)
5954152G alpha (i) signalling events
5953642GPCR downstream signaling
5953758GPCR ligand binding
5954121Peptide ligand-binding receptors
5953391Signaling by GPCR
5953381Signal Transduction