LMPD Database

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LMP012984

UniProt Annotations

Entry Information
Gene Nameoxysterol binding protein-like 1A
Protein EntryOSBL1_RAT
UniProt IDQ8K4M9
SpeciesRat
Comments
Comment typeDescription
FunctionBinds phospholipids; exhibits strong binding to phosphatidic acid and weak binding to phosphatidylinositol 3- phosphate. Stabilizes GTP-bound RAB7A on late endosomes/lysosomes and alters functional properties of late endocytic compartments via its interaction with RAB7A
SimilarityBelongs to the OSBP family
SimilarityContains 1 PH domain. {ECO:0000255|PROSITE- ProRule:PRU00145}.
SimilarityContains 3 ANK repeats. {ECO:0000255|PROSITE- ProRule:PRU00023}.
Subcellular LocationLate endosome . Note=Co- localizes with RAB7A, RAB9A and LAMP1 in late endosomes
SubunitInteracts with VAPA. Interacts with the GTP-bound form of RAB7A (By similarity). Interacts with OAS1B (By similarity)
Tissue SpecificityDetected in prostate and liver