LMPD Database

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LMP013036

UniProt Annotations

Entry Information
Gene Nameacyl-CoA binding domain containing 3
Protein EntryGCP60_RAT
UniProt IDQ7TNY6
SpeciesRat
Comments
Comment typeDescription
DomainThe GOLD domain is essential for giantin binding
FunctionInvolved in the maintenance of Golgi structure by interacting with giantin, affecting protein transport between the endoplasmic reticulum and Golgi. Involved in hormone-induced steroid biosynthesis in testicular Leydig cells (By similarity)
SimilarityContains 1 ACB (acyl-CoA-binding) domain
SimilarityContains 1 GOLD domain. {ECO:0000255|PROSITE- ProRule:PRU00096}.
Subcellular LocationGolgi apparatus membrane ; Peripheral membrane protein ; Cytoplasmic side {ECO:0000250}. Mitochondrion . Note=Also mitochondrial (via its interaction with PBR)
SubunitInteracts with the C-terminal cytoplasmic domain of giantin/GOLGB1. Interacts with PBR and PKA regulatory subunit RI- alpha. Does not interact with PKA regulatory subunit RI-beta nor PKA regulatory subunit RII-alpha (By similarity)